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Pronucleus is an important aspect of fertilization and plays a crucial role in the development of embryos. After the sperm enters the egg cell, it loses its membrane and tail, and becomes a pronucleus. The egg cell also becomes a pronucleus, but only after it becomes haploid, which means it has half the usual number of chromosomes.

The appearance of two pronuclei is a sign of successful fertilization and is observed during in vitro fertilization after around 18 hours of insemination or ICSI. This stage is called a two-pronuclear zygote (2PN). Embryos that remain 2PN throughout development tend to have better quality and higher chances of successful implantation and pregnancy.

However, in some cases, the zygote may transition through 1PN or 3PN stages, which can result in poorer quality embryos. This is significant in the selection of embryos during in vitro fertilization, as it helps identify which embryos have the best potential for successful pregnancy.

At Aashakiran IVF, we use advanced technologies to monitor and analyze the development of embryos to ensure the highest chances of success for our patients undergoing fertility treatments. Our team of experienced doctors and embryologists work together to provide personalized and comprehensive care to our patients, helping them achieve their dream of parenthood.