Controlled ovarian hyperstimulation (COH) is a process used in assisted reproductive technology (ART) to stimulate the ovaries to produce multiple follicles containing eggs. This is done through the administration of fertility medications, which can be given as injections or pills. The goal of COH is to increase the chances of pregnancy by increasing the number of eggs available for fertilization.
During COH, the development of follicles is closely monitored through ultrasound and blood tests to determine the optimal time for ovulation. Ovulation can be triggered through the use of medications such as human chorionic gonadotropin (hCG), which stimulates the release of eggs from the follicles.
Once the eggs have been released, they can be retrieved through a minimally invasive procedure known as oocyte retrieval. The eggs are then fertilized in the laboratory using in vitro fertilization (IVF) techniques.
COH carries a risk of ovarian hyperstimulation syndrome (OHSS), a potentially serious complication in which the ovaries become swollen and painful due to the excess production of follicles. OHSS can be managed through close monitoring and, in severe cases, hospitalization.
COH can also increase the risk of multiple pregnancies, which carry their own set of risks and complications. To mitigate this risk, fertility specialists may choose to transfer fewer embryos during IVF or to freeze unused embryos for future use.
AASHAKIRAN IVF is a leading fertility clinic in India that offers a range of assisted reproductive techniques, including COH and IVF, to help couples struggling with infertility achieve their dream of parenthood.