Laser assisted hatching is a scientific IVF technique that can make it easier for the embryo to “hatch” or breakthrough its outer layer or shell or zona pellucida.
Implantation failure can be due to zona pellucida hatching failure after blastocyst expansion. Thick zona pellucida (more than 16mm) high follicle stimulating hormone level and advanced age is possible region for hatching failure. It has been recorded that human hatched blastocyst can predict there implantation behavior. Transferring of blastocyst hatched closed to ICM scientifically higher clinical pregnancy rate (72%) as compared to that which are close to trophectoderm (51%). Assisted hatching may techniques are mechanical, chemical, piezo technology and laser assisted hatching.
Laser assisted hatching might help improve pregnancy chances for certain group of patients. Assisted hatching may help to improve pregnancy chances in women who have failed to get pregnant in last IVF cycles and those with a poor prognosis.