It involves checking the checking the chromosome of embryo created by in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) for abnormalities. PGS doesn’t check for specific genetic diagnosis. During PGS, a single cell or small number of cells is removed from the embryo. The DNA of these cell then testes to see whether they have any chromosomal abnormalities. Only embryo without chromosomal abnormalities is placed back in the womb.
Older women are more likely to have egg with the wrong number of chromosome. Abnormal chromosome is thought to be the main reason why older women have difficulties conceiving or a baby with Down’s syndrome. PGS involves taking a biopsy, to remove a cell of number of cells; from an embryo which can sometime cause damage to embryo and prevent it from developing once it has been transferred into the womb.
This test may be recommended if patient have some family history of chromosomal problems, if your sperm is at risk of carrying abnormal chromosome or if you had several miscarriages or failed IVF attempts without explanation.