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Physiological Intracytoplasmic Sperm Insemination (PICSI) is an advanced assisted reproduction technique used for selecting mature and structurally normal spermatozoa for insemination. This procedure is more precise than the basic ICSI and IVF techniques. PICSI is used in the diagnosis of male infertility caused by genetic or environmental factors.

PICSI involves the selection of a mature sperm with genetically intact and compact DNA, which is separated from other sperm using hyaluronic acid (HA) binding. This process minimizes the risk of fertilization failure due to sperm with morphologically normal structures but higher levels of damaged DNA. The selected sperm is then injected into the oocyte, similar to the ICSI procedure.

The main advantage of PICSI is that it allows for the selection of mature and genetically intact sperm, reducing the risk of pregnancy failure and congenital anomalies. In Aashakiran Fertility World, routine semen analysis and functional tests are conducted to ensure that the best treatment options are provided to patients. The skilled IVF doctors and team at the hospital strive to fulfill the patient's requirements using the latest and most advanced techniques available.

PICSI is recommended for males with a history of genetic diseases or ejaculatory dysfunctions and severe infertility issues. Females with a history of multiple abortions or previous IVF failures and both males and females with advanced age can also opt for this technique. Overall, PICSI is a safe and effective assisted reproduction technique that can increase the chances of a successful pregnancy for couples struggling with infertility.