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Physiological Intracytoplasmic Sperm Insemination (PICSI)

Physiological Intracytoplasmic Sperm Insemination (PICSI)

PICSI is a process that is a part of assisted reproduction technique which is advance and precise than ICSI and IVF. This is a next version to ICSI technique selection of mature and structurally normal spermatozoa from the pool of sperms that is used for insemination. It is a procedure which is used in diagnosis of male infertility that are induced either environmentally or genetically.

How it is done?

PICSI involves selection of a mature individual sperm which has compact genetically integrity helping separation of that specific sperm from others with. Sometime immature sperms can show morphologically normal structure with motility but may have higher level of damaged DNA constituents which effect fertilization outcome. So to avoid such situation PICSI is a method that allows sperm selection having Hyaluronic Acid (HA) binding receptor that binds with hyaluronic acid site in PICSI dish which is used in treatment. It is similar to ICSI procedure where Oolemma is ruptured then selected sperm is injected in the oocyte.


In ART ICSI is a basic form of single sperm selection method for in-vitro fertilization aiding in viable sperm selection that is morphologically superior among others. It is an innovative method for sorting mature sperms which minimizes the risk of pregnancy failure such as stillbirth, spontaneous miscarriages and congenital anomalies. Along with such advance technique in Aashakiran Fertility World we do routine semen analysis and its functional tests if required. In our hospital we try to fulfill patient’s requirement with enhanced technique and killed IVF doctors and team ensuring best services to patients.

Who can opt for this?

  1. Male with history of genetic disease.
  2. Male with ejaculatory dysfunctions.
  3. Male with severe infertility issues.
  4. Female with history of multiple abortion.
  5. Female with history of previous IVF failure.
  6. Female/Male with advance age.