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Does Age Effect On Infertility

Does age effect on infertility

Fertility decreases with age, particularly after the age of 35 because both the number and quality of eggs gets lower. An egg is sent from your ovaries to your womb every month from when you hit puberty to the menopause. Woman is born with all the eggs she is going to have in her lifetime. Eggs decreased in quality and quantity with age. The maximum complement of oocytes is 6–7 million and exists at 20 weeks of gestation in the female fetus. The number of oocytes decreases to approximately 1–2 million oocytes at birth; 300,000–500,000 at puberty; 25,000 at age 37 years; and 1,000 at age 51 years, Age is the single most important factor affecting a woman’s fertility. While good health improves the chance of getting pregnant and having a healthy baby; it doesn’t override the effects of age on a woman’s fertility.

The number and quality of eggs which is called ovarian reserve decreases naturally and progressively from the time a woman is born until the time she reaches menopause. This decline is gradual until her early 30s but accelerates quickly after her mid-30s. It is not only more difficult to get pregnant but miscarriage and chromosomal abnormalities in the child are more common in older mothers.

To check the egg quality and quantity there are some hormonal blood tests like FSH, LH and AMH. Doctor also performed follicular study with ultrasonography to check the status of follicles.

        Age               Number of Genetically abnormal embryos

  • 25-30         25%
  • 31-35         35%
  • 35-37         45%
  • 38-40         60%
  • 41-43         80%
  • ≥44            >80% to 90%

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