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Unsafe Antibiotics in Pregnancy

               

Prescribing antibiotics in pregnant patient is a special consideration, because we should consider the effects of these antibiotics not just on the mother but also on to the fetus. Antibiotics should not be prescribed during first trimester and to be more specific we should not prescribe antibiotics between 18 to 60 days of pregnancy. This is because at this time embryo is very much susceptible to various territorial occasions.

Unsafe Antibiotics such as

  1. Macrolides
  2. Quinolones
  3.  Tetracyclines
  4.  Sulfonamides
  5. Metronidazole
  6. Ciprofloxacin
  • Tetracyclines can discolor a developing baby's teeth. Tetracyclines aren't recommended for use after the 15th week of pregnancy.
  • Ciprofloxacin could cause problem with baby’s muscle and skeletal growth as well as joint pain. And potential nerve damage in mother
  • Fluroquinolone can increase risk of aortic rupture. This can result in life threatening bleeding. May also increase chance of having miscarriage.
  • Sulfa drugs can cause jaundice in newborns.
  • Trimethoprim can cause neural tube defects.
  • Ibuprofen can cause delayed onset of labor, abnormal vitamin k levels and jaundice.
  • Metronidazole it should not prescribe in 1st trimester as it can cause fetal damage.
  • Erythromycin estolate form of erythromycin can cause hepatotoxicity.It causes swelling of cells lining billiary canaliculi within the liver.

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