This refined and advance technique first stepped in the ART world in 1992, with the help of which first ICI baby was born on 14/01/1992. It was invented by Professor André Van Steirteghem in the Centre for Reproductive Medicine at the Vrije Univesiteit Brussel, Belgium.
ICSI is intracytoplasmic sperm injection technique where one morphologically normal spermatozoon is selected in washed semen sample that is injected in oocyte by puncturing zona pellucida and allow to fuse to form zygote on next day. It is a most suggested method of treatment for couple with male infertility problems or having history of IVF failure despite of all normal diagnosis.
The process of ICSI enhances the chance of fertilization in couple facing problem in conceiving especially with severe male fertility factor. There are various male factors that effects the pregnancy outcome in couple such as
How ICSI is done?
Moreover, ICSI along with DFI can reduce the chances of chromosomal abnormality in children. Also, being an advance method fertilization rate is enhanced with the help of ICSI.